product-listing

SV-ARB®

BRAND NAME:

 

  • SV-ARB 50/100 Tablets

     

    Composition:  Sacubitril 24mg + Valsartan 26mg  |  Sacubitril 49mg + Valsartan 51mg

     

    PACKING:   1x10

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INDICATED IN:

Sacubitril-valsartan is prescribed to manage patients with heart failure with preserved ejection fraction (HFpEF). Sacubitril-valsartan is also FDA-approved for pediatric patients with heart failure.

Mode of Action

  • SACUBITRIL

    Sacubitril is a pro-drug that, upon activation, acts as a neprilysin inhibitor. The drug works by blocking the action of neprilysin, preventing the breakdown of natriuretic peptides, which leads to a prolonged duration of the favorable effects of these peptides.

  • VALSARTAN

    Valsartan is an angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.

    Benefits & Usage

    The benefits of sacubitril/valsartan in HF patients are felt to be due to the increased levels of peptides that are degraded by neprilysin and the simultaneous inhibition of the effects of AT1 receptor by valsartan.

    Precautions

    warnings Alcohol

    It is unsafe to consume alcohol with SV-ARB Tablets.


    warnings Pregnancy

    Make sure your doctor knows if you are pregnant or planning to become pregnant.


    warnings Medicine

    Do not take other medicines unless they have been discussed with your doctor.


    warnings Liver & Kidney

    Should be used with caution in patients with liver & kidney disease.