Dartsita-D 5/10/50/100
BRAND NAME: Dartsita - D5/D10/D50/D100
PACKING: 1x10
INDICATED IN: In Type 2 Diabetes Mellitus
Mode of Action
Dartsita-D is a combination of two anti-diabetic drugs namely Dapagliflozin and Sitagliptin
Sitagliptin: Sitagliptin increases insulin production and decreases hepatic glucose overproduction. Sitagliptin prolongs the action of GLP-1 and GIP. By enhancing active incretin levels, sitagliptin increases insulin production and lowers glucagon secretion from alpha cells, which decreases hepatic glucose overproduction.
Dapagliflozin: By inhibiting SGLT2, dapagliflozin blocks reabsorption of filtered glucose in the kidney, increasing urinary glucose excretion and reducing blood glucose levels. Its mechanism of action is independent of pancreatic β cell function and modulation of insulin sensitivity.
Sitagliptin: Sitagliptin increases insulin production and decreases hepatic glucose overproduction. Sitagliptin prolongs the action of GLP-1 and GIP. By enhancing active incretin levels, sitagliptin increases insulin production and lowers glucagon secretion from alpha cells, which decreases hepatic glucose overproduction.
Dapagliflozin: By inhibiting SGLT2, dapagliflozin blocks reabsorption of filtered glucose in the kidney, increasing urinary glucose excretion and reducing blood glucose levels. Its mechanism of action is independent of pancreatic β cell function and modulation of insulin sensitivity.
Benefits & USAGE
Dapagliflozin + Sitagliptin is used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications. It also reduces the risk of heart attack, heart failure or other cardiovascular events.
Precautions
Alcohol
Avoid drinking alcohol. It may cause hypoglycemia (low blood sugar level).
Pregnancy
Make sure your doctor knows if you are pregnant or planning to become pregnant.
Medicine
Do not take other medicines unless they have been discussed with your doctor.
Liver & Kidney
Should be used with caution in patients with liver & kidney disease.
