

DARTMET®
BRAND NAME:
- Dartmet 500/1000 Tablets
Composition: Metformin (SR) 500/1000 mg
PACKING: 1x15
- Dartmet G1/G2 Tablets
Composition: Metformin HCl 500mg (SR) + Glimepiride 1/2 mg
PACKING: 1x15
- Dartmet G1/G2/G3/G4 Forte Tablets
Composition: Metformin HCl 1000mg (SR) + Glimepiride 1/2/3/4 mg
PACKING: 1x15
- Dartmet PG1/PG2 Tablets
Composition: Metformin HCl 1000mg (SR) + Pioglitazone 15 mg + Glimepiride 1/2/3/4 mg
PACKING: 1x15
- Dartmet VG1/VG2 Tablets
Composition: Metformin HCl 1000mg (SR) + Voglibose 0.2 mg + Glimepiride 1/2/3/4 mg
PACKING: 1x15
INDICATED IN:
Type II Diabetes Mellitus
Mode of Action
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Metformin
Belongs to a class of drug called as Biguanides. It is used to treat type 2 diabetes mellitus. It works by decreasing the glucose production by inhibiting gluconeogenesis and glycogenolysis in liver.
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Glimepiride
Belongs to a class of drug called as Sulphonylurea. It is used to treat type 2 diabetes mellitus. It acts as insulin secretion enhancer. It works by increasing the amount of insulin released by the pancreas in order to lowers the blood glucose level.
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Pioglitazone
Belongs to a class of drug called as Thiazolidinediones. It is used to treat type 2 diabetes mellitus. It acts as insulin sensitizer. It enhances insulin sensitivity in peripheral tissues and liver by activation of PPAR-gamma receptors (Peroxisome proliferator -activated receptor gamma) & improving peripheral uptake and utilization of glucose in muscle and fat, finally decreasing liver glucose production.
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Voglibose
Voglibose is an alpha-glucosidase inhibitor which slows the digestion and absorption of carbohydrates resulting in improvement of post-prandial hyperglycemia.
Benefits & Usage
Metformin is used as a first-line therapy for T2DM as it reduces glucose production in liver thereby reducing Blood Glucose levels.
Precautions
Alcohol
It is not safe to consume alcohol with Dartmet 500/1000, Dartmet G1/G2, Dartmet G1/G2/G3/G4 Forte, Dartmet PG1/PG2, Dartmet VG1/VG2 Tablets
Pregnancy
Make sure your doctor knows if you are pregnant or planning to become pregnant.
Medicine
Do not take other medicines unless they have been discussed with your doctor.
Liver & Kidney
It should be used with caution in patients with liver & kidney disease.