DARTDAPA®
BRAND NAME:
- Dartdapa 5/10 Tablets
Composition: Dapagliflozin5/10mg
PACKING: 1x15
- Dartdapa-M 500/Forte
Composition: Dapagliflozin 10 mg+Metformin Hydrochloride (ER) 500/1000 mg
PACKING: 1x10
- Dartdapa-V 5/100 & 10/100
Composition: Dapagliflozin 5/10mg+Vildagliptin100mg
PACKING: 1x10
INDICATED IN:
Type II Diabetes Mellitus
Mode of Action
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Dapagliflozin
Dapagliflozin belongs to a class of medicines called SGLT2 (sodium glucose transporter 2) inhibitor. SGLT2 channel mainly present in kidney (nephron) responsible for the 90% glucose reabsorption in the body. Dapagliflozin blocks SGLT2 channel & decreases the reabsorption of glucose, increases glucose excretion through urine
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Metformin
Belongs to a class of drug called as Biguanides. It is used to treat type 2 diabetes mellitus. It works by decreasing the glucose production by inhibiting gluconeogenesis and glycogenolysis in liver.
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Vildagliptin
Vildagliptin is a DPP4 Inhibitor which reduces the amount of glucose produced by the liver, by raising insulin levels and decreasing the levels of the glucagon (the hormone that increases blood glucose level).
Benefits & Usage
Dapagliflozin is well-tolerated and safe as noted in older patients, patients with poorly controlled diabetes, those with heart failure or CV risk factors. Dapagliflozin also improves glycemic control in patients with poorly controlled T2DM.
Precautions
Diuretic
It is unsafe to consume alcohol with Dartdapa Tablets, Dartdapa-M &Dartdapa-V Tablets.
Water
Make sure your doctor knows if you are pregnant or planning to become pregnant.
Pregnancy
Do not take other medicines unless they have been discussed with your doctor.
Medicine
Should be used with caution in patients with liver & kidney disease.
