ATAXIA-G400®

INDICATED IN:

In neuropathic pain (pain in damaged nerves).

• Gabapentin

  Gabapentin is a ligand of α2δ calcium channel subunit. Gabapentin appears to inhibit the action of α2δ-1 subunits, thus decreasing the density of pre synaptic voltage-gated calcium channels and subsequent release of excitatory neurotransmitters. It is likely that this inhibition is also responsible for the anti-epileptic action of gabapentin.

• Nortryptyline

  Nortriptyline exerts antidepressant effects likely by inhibiting the reuptake of serotonin and norepinephrine at neuronal cell membranes. It also exerts antimuscarinic effects through its actions on the acetylcholine receptor.

ATAXIA-G400 a combination of Gabapentin or Nortriptyline may work better than either drug alone. It shows synergistic effect in people who experience neuropathic chronic pain (pain from damaged nerves)